Which condition is listed as a caution with ibuprofen use?

Which condition is listed as a caution with ibuprofen use?

• A. N/V
• B. Hypersensitivity
• C. Route: PO
• D. Recent GI bleeding

Answer: (D)

Ibuprofen is an NSAID that lowers prostaglandin production, which normally helps protect the stomach lining and support mucosal healing and clot formation. In someone with recent GI bleeding, this can worsen bleeding and impede healing because the protective lining is compromised and platelet function is affected. That’s why recent GI bleeding is a significant caution for ibuprofen use. Nausea or vomiting can occur with NSAIDs, but they are not a condition that by themselves mandates avoidance. Route of administration (oral) is just how the drug is given, not a health condition. Hypersensitivity would also be a reason to avoid, but the scenario specifically highlights GI bleeding as the caution.

Ibuprofen is an NSAID that lowers prostaglandin production, which normally helps protect the stomach lining and support mucosal healing and clot formation. In someone with recent GI bleeding, this can worsen bleeding and impede healing because the protective lining is compromised and platelet function is affected. That’s why recent GI bleeding is a significant caution for ibuprofen use.

Nausea or vomiting can occur with NSAIDs, but they are not a condition that by themselves mandates avoidance. Route of administration (oral) is just how the drug is given, not a health condition. Hypersensitivity would also be a reason to avoid, but the scenario specifically highlights GI bleeding as the caution.